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Hold the dose steady for 2 weeks before adjusting
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BPC-157 shows remarkable stability and can be administered orally with some retained activity, unlike most peptides which degrade in the digestive system
29 Due to its importance in the synthesis of myelin and neurotransmitters, as well as in keeping homocysteine levels low, all of which are associated with cognitive function, B12 has been studied for a potential role in cognitive function
hospitalization required Maintenance of Remission: Immunomodulators (azathioprine, 6-MP, methotrexate) for steroid-dependent or frequently-relapsing disease Biologic monotherapy or combination therapy (biologic + immunomodulator) for moderate-to-severe disease Step-up or top-down approach based on disease severity, patient risk factors, and prior therapy Biologic Therapy Targets: TNF-: Infliximab (IV), adalimumab (SC), certolizumab pegol (SC) IL-12/23: Ustekinumab (IV induction, SC maintenance) Integrin: Vedolizumab (IV) IL-23: Risankizumab (IV induction, SC maintenance) JAK inhibition: Upadacitinib (oral) Surgical Management Surgery is indicated in approximately 7080% of patients with Crohns disease over their lifetime, per StatPearls
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